Global Media Giants

Global nutrient transport in a world of giants.

The past was a world of giants, with abundant whales in the sea and large animals roaming the land. However, that world came to an end following massive late-Quaternary megafauna extinctions on land and widespread population reductions in great whale populations over the past few centuries. These losses are likely to have had important consequences for broad-scale nutrient cycling, because rece...

Frailty: joining the giants.

Since Isaacs made that statement, further giants of geriatric medicine, such as iatrogenesis, have been added to the list. The concept of geriatric syndromes has been universally accepted with internationally agreed-upon definitions and numerous guidelines for assessment and treatment. The last decade has seen a burgeoning interest in yet another giant: the frailty syndrome. Frailty can be thou...

“Giants in a Microcosm”

On examination of a breast mass surgically excised in a 69-years-old woman, a pure invasive micropapillary carcinoma (MPC) was diagnosed (Figure 1). At close examination, intensely eosinophilic syncytial-multinucleated giant cells (CD68+) percolating the stromal bands were identified (Figure 1). The breast carcinoma illustrated here shows therefore a combination of 2 rarities, namely, an invasi...

The Cardboard Giants

This is a record of the experiences in a mental hospital of a patient suffering (apparently) from paranoid schizophrenia. As it is stated on the cover that the patient has recovered from his illness and that he has written the book under his own name, it is very difficult to make any comment from the clinical point of view without running the risk of doing harm. He himself has recorded and disc...

the shoulders of Giants